Formaldehyde-Free Fixative Solution

Seven small jars of FIXUP Solution stacked in a pyramid formation on a white background.

FIXUP Solution®

A next-generation fixative designed to preserve tissue for histology laboratory use — without formaldehyde.

FIXUP Solution is a formaldehyde-free fixative for histology laboratory use, designed to replace 10% Neutral Buffered Formalin. Its chemical composition comprises safe materials that comply with current safety and environmental standards.

FIXUP Solution penetrates tissue more quickly yet fixes more gently than formalin, minimizing tissue damage for more precise histological reading. It also preserves DNA at levels comparable to 70% ethanol fixation — significantly outperforming 10% NBF — enabling H&E, immunohistochemistry, and molecular diagnostics from a single fixative.

e-Catalog

“Coming in 2027”

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Key Facts

  • Compatible with H&E and IHC staining.

  • Contains zero formaldehyde — not even 0.1%.

  • Fully compatible with 10% Neutral Buffered Formalin.

This is the fact

The only way to truly eliminate formaldehyde exposure in the laboratory is to eliminate formaldehyde itself.

Staining Results

  • Microscopic cross-section of a brain tissue sample stained with purple dye, showing distinct layers and cell structures.

    Brain

    Rabbit, FIXUP Solution, fixing 6h

  • Histological tissue sample stained with hematoxylin and eosin showing glandular structures and connective tissue.

    Pituitary gland

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic view of tissue with pink and purple staining, showing dense muscle fibers and scattered structures.

    Heart

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic image of muscle tissue stained pink and purple with a smaller inset image of a cross-section of a tree trunk showing growth rings.

    Kidney

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic view of a biological tissue sample stained pink, showing cellular structures and tissue organization.

    Liver

    Rabbit, FIXUP Solution, fixing 6h

  • Histology slide showing bone tissue with trabeculae and marrow spaces, stained with hematoxylin and eosin.

    Lung

    Rabbit, FIXUP Solution, fixing 6h

  • Histology slide showing tissue with dense cell nuclei stained purple, with inset of a smaller close-up view of tissue cells.

    Thymus

    Rabbit, FIXUP Solution, fixing 6h

  • Histology slide with purple-stained tissue and a small inset image of another tissue sample in the top left corner.

    Spleen

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic view of tissue with inset showing a gross specimen of two small, irregular-shaped tumors.

    Submandibular gland

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic view of bone marrow tissue with fat cells and hematopoietic cells in purple and pink stain.

    Parotid gland

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic image of thyroid tissue showing dense lymphoid follicles and colloid-filled follicles.

    Thyroid gland

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic view of a tissue sample showing intestinal lining with villi, stained in pink and purple hues.

    Stomach

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic image of biological tissue stained in purple, showing intricate glandular or follicular structures typical of tissue samples, with an inset diagram of a cross-section of a follicle or gland.

    Small intestine

    Rabbit, FIXUP Solution, fixing 6h

  • Close-up of a biological tissue sample stained with purple dye, showing glandular structures and cellular details. An inset in the top left corner displays a smaller, separate microscopic image of glandular tissue.

    Large intestine

    Rabbit, FIXUP Solution, fixing 6h

  • Bladder

    Bladder

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic image of tissue sample stained with hematoxylin and eosin, showing glandular structures, fibrous tissue, and cellular features. Inset shows cross-sections of kidney tissue stained similarly, depicting renal tubules and glomeruli.

    Vagina

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic view of a tissue sample, showing glandular structures and surrounding supportive tissue, stained with H&E stain.

    Ovary

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic cross-section of a plant leaf stained with purple dye, showing vascular tissue and cell structures.

    Tongue

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic view of a skeletal muscle tissue stained with H&E, showing muscle fibers with striations and connective tissue.

    Sciatic nerve

    Rabbit, FIXUP Solution, fixing 6h

  • Abstract digital artwork featuring predominantly pink and purple hues with a broken colonial-era teacup in the top left corner and a distorted, circular shape in the center.

    Eyeball

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic image of plant root cells stained in purple and pink, showing root hair zone with elongated root hairs and surrounding tissue.

    Skin

    Rabbit, FIXUP Solution, fixing 6h

  • Microscopic image of rat brain tissue stained with purple dye, showing granular cellular structures.

    Spinal cord

    Rabbit, FIXUP Solution, fixing 6h

  • Close-up of a microscope slide showing a cross-section of a fish's fin with bone, cartilage, and connective tissue, with an inset of a whole fish specimen highlighting its elongated body and fins.

    Trachea

    Rabbit, FIXUP Solution, fixing 6h

  • Histological image of a hair follicle structure, stained with purple and pink hues, including surrounding skin tissue and hair root.

    Esophagus

    Rabbit, FIXUP Solution, fixing 6h

Product Number

  • FIXUP Solution, Prefilled 20mL, 96/Cs

  • FIXUP Solution, 1000mL, 4/Cs

  • FIXUP Solution, 1gal., 4/Cs

  • FIXUP Solution, 5gal., Cube

Request Sample

Your first step to eliminating formaldehyde from the lab.