Xylene-Free Clearing Reagent
XUP™
XUP™ is a xylene-free clearing reagent designed for tissue processing and staining applications. It can replace xylene in most histology and cytology laboratories without significant procedural changes. Its lower toxicity profile reduces chemical hazard exposure for laboratory personnel and simplifies hazardous waste disposal. Switch to XUP™ to create a safer, healthier workplace — without compromising staining quality.
“Coming August 2026”
This is the fact
The only way to truly eliminate xylene exposure in the laboratory is to eliminate xylene itself.
Product Number
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XUP™ Xylene Substitute, 1000mL, 4/Cs
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XUP™ Xylene Substitute, 1gal., 4/Cs
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XUP™ Xylene Substitute, 5Gal., Cube
Request Sample
Your first step to eliminating xylene from the lab.

