FIXUP Solution®

An ethanol-based tissue fixative designed to replace 10% neutral buffered formalin, with zero formaldehyde. One fixative supports H&E, IHC, and DNA-based molecular testing.

Planned U.S. launch: 2027

Catalog No.	Size	Pack
TFX1002	20 mL prefilled	96 / case
TFX1010	1000 mL	4 / case
TFX1038	1 gal	4 / case
TFX1085	5 gal	Cube

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OverviewSpecificationsSafety & ShippingCompatibility

Zero formaldehyde. Contains no formaldehyde, not even 0.1%. No formaldehyde at the grossing bench or in specimen containers.
Better DNA preservation. Preserves DNA at levels comparable to 70% ethanol fixation, significantly outperforming 10% NBF.
Gentle fixation. Penetrates tissue quickly and fixes gently, minimizing tissue damage for precise histological reading.
One fixative, three workflows. H&E, immunohistochemistry, and molecular diagnostics from the same specimen.

Composition	Ethanol-based, formaldehyde-free mixture. Hazardous components are listed in SDS Section 3.
Appearance / odor	Clear, colorless to pale yellow liquid / alcohol-like
pH	Approx. 4
Boiling point	83 °C (181.4 °F)
Flash point	24 °C (75.2 °F)
Water solubility	Miscible
Storage	Cool, dry, well-ventilated place away from heat and ignition sources. Keep tightly closed and store locked up. Reseal opened containers and keep them upright.
Materials to avoid	Strong oxidizing agents, strong bases, amines, and some rubbers and plastics

Signal word	Warning
Hazard statements	H226, H319, H317, H341
NFPA (Health / Fire / Reactivity)	2 / 3 / 0
DOT / IATA / IMDG	UN1170, Ethanol solution, Class 3, PG III
Waste	May be classified as ignitable hazardous waste (EPA D001). Dispose of according to federal, state, and local regulations.

Staining	Compatible with H&E and IHC, including Ki-67.
Molecular testing	DNA preserved at levels comparable to 70% ethanol fixation.
10% NBF	Fully compatible with 10% neutral buffered formalin.
Protocol setup	Contact our technical team for fixation time and processor settings for your specimen types.