Our Commitment to a Safer Laboratory

Behind every diagnosis are people the patient never meets. We exist for them.

What We Supply

Two Product Lines for Histology Labs

U.S. Exclusive Distributor

GDxDORCO Microtome Blades

FIXUP Biochemical is the exclusive U.S. distributor of GDxDORCO microtome blades. High-alloy stainless steel blades engineered for consistent, high-quality sectioning in routine and research histology.

Explore GDxDORCO Blades →

Safer Chemistry

Histology Reagents

Formalin-free and xylene-free reagents that help laboratories reduce chemical exposure across fixation, clearing, and mounting.

  • FIXUP Solution — formalin-free fixative
  • XUP — xylene-free clearing solution
  • XUP Mount — xylene-free mounting medium
View Reagents →
A man wearing a green beanie and red shirt, with his eyes closed and hands covering his eyes, appearing to be in distress or deep thought.

Is your research harming you more than you realize?

Formaldehyde

is classified as a Group 1 carcinogen by the IARC.

Formaldehyde is classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC), indicating sufficient evidence of carcinogenicity in humans. Exposure to formaldehyde is associated with severe irritation of the eyes, nose, and respiratory tract, asthma, chronic bronchitis, and an increased risk of cancers such as nasopharyngeal and sinus cancer.

Xylene

A hazardous solvent widely used in histology laboratories

Xylene is commonly used as a clearing agent in histology, but prolonged exposure can affect the central nervous system and cause irritation of the eyes, skin, and respiratory system. Chronic exposure may lead to headaches, dizziness, and neurological symptoms, making laboratory safety and exposure reduction increasingly important.

Safer Chemistry for Histology Laboratories

FIXUP Solution and XUP Products help laboratories move away from hazardous chemicals such as formalin and xylene while improving the laboratory working environment.

FIXUP SOLUTION

A Formalin-Free Fixative for Safer Laboratories

Providing a safer alternative to hazardous chemicals while improving the laboratory working environment.

Stack of clear jars with white lids labeled 'FIXUP Solution' in green and white, arranged in a pyramid formation on a white surface with a plain white background.
Learn More

XUP

Xylene-Free Clearing Solution

Two bottles of XUP Xylene-Free Clearing Reagent, one 1-liter bottle and one 1-gallon bottle, both with white labels and green and black text, on a white background.

A safer alternative to xylene designed to reduce chemical exposure and improve the laboratory working environment.

Learn More

XUP Mount

Xylene-Free Mounting Medium

Two bottles of XUP mounting medium, a smaller one with a white nozzle and a larger one with a green lid, both labeled with product information and a green and white design.

A xylene-free mounting medium designed to support safer histology workflows and improved laboratory environments.

Learn More

Healthcare Workers Are

Family Members Too

Family of four smiling and hugging outdoors in a park.

Laboratory professionals should not have to worry about breathing in hazardous chemicals at work.

Move Toward Safer Chemistry

  • FIXUP Solution™

    A formalin-free fixative solution developed for histology laboratory use. The formulation is composed of carefully selected components that comply with safety and environmental standards. It provides a safer alternative to formalin while maintaining reliable tissue fixation performance.

  • Two clear plastic bottles of XUP Xylene-Free Clearing Reagent, one small and one large, with white labels featuring green and black text, set against a white background.

    XUP™

    XUP™ is a clear reagent designed to replace xylene in histology processing and staining applications. It provides a safer alternative for laboratory use and disposal. In most histology and cytology laboratories, it can substitute for xylene without significant changes to existing procedures.

  • Two bottles of XUP mounting medium, one smaller with a white nozzle, the other larger with a green cap, both labeled with product information against a white background.

    XUP™ Mount

    XUP™ Mounting Medium is a clear mounting medium developed for xylene-free histology mounting applications. It provides a safer alternative for laboratory use and disposal. In most histology and cytology laboratories, it can be used without significant changes to existing procedures.

  • Various sizes of clear plastic specimen containers with white screw-on lids, labeled with 'PathoLock' and color-coded labels, on a white background.

    PathoLock™

    A sealed formalin container designed to prevent direct contact with fixative during specimen handling. A simple twist activates the internal mechanism to release formalin into the container, reducing exposure risks while supporting safe and reliable tissue fixation workflows.

Request Sample